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The rise of CSC theory, some specific CSC markers were being discovered to identify putative CSCs, and ALDH1 is becoming to act as a CSC marker in the CSC studies of variable tumor types in vitro and in vivo. Epithelial-to-mesenchymal transition (EMT) is an important driver of tumor invasion and metastasis, which may be a feature of CSC. Compared to ALDH1(-) EMT cells, only ALDH1(+) EMT cells had
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Gnosis of ODD with fewer than 4 ODD symptoms. Nevertheless, all youth with 3 AIS also exhibited at least one NS in the present sample. Given that the DSM model may under-identify youth with impairing ODD,30,31 future research should evaluate the prevalence of youth with AIS who do not meet criteria for ODD, as well as multiple models for considering ODD symptoms and diagnoses (e.g., DSM, ICD). Acr
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Urce patches can (and may well be likely to) evolve intoUrce patches can (and may well be likely to) evolve into and be maintained as a polymorphic foraging-strategy guild.Supporting InformationS1 Table. (PDF)PLOS ONE | DOI:10.1371/journal.pone.0133732 August 14,20 /Evolution of Foraging Guilds on Patchy ResourcesS1 Text. (PDF) S2 Text. (PDF) S3 Text. (PDF) S4 Text. (PDF)AcknowledgmentsWe th
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Such models. We have demonstrated here that the Nova platform isSuch models. We have demonstrated here that the Nova platform is moving us towards these desired software capabilities. As a result of reducing the considerable burden of coding complex agent-based models and casting them within a genetic algorithmic framework that now is easily implemented using the Nova platform, in the future
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Etc. [34, 35]. However, it still remains challenging to identify one single marker or several combined markers to specifically identify all the CSCs in ovarian tumor, and the exact roles of these `stemness' related markers, are still poorly understood due to either a current lack of understanding of the biological functions of the markers, or frequently the lack of information correlating the vari